3-Indoleacetic acid-d7

Names

[ CAS No. ]:
1173020-21-7

[ Name ]:
3-Indoleacetic acid-d7

[Synonym ]:
1H-Indole-2,4,5,6,7-d-3-acetic-d acid
(2,4,5,6,7-H)-1H-Indol-3-yl(H)acetic acid

Biological Activity

[Description]:

3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
415.0±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H2D7NO2

[ Molecular Weight ]:
182.227

[ Flash Point ]:
204.8±21.8 °C

[ Exact Mass ]:
182.107269

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.694

Related Compounds