Sperabillin A dihydrochloride

Names

[ CAS No. ]:
111337-87-2

[ Name ]:
Sperabillin A dihydrochloride

[Synonym ]:
Sperabillin C
Sperabillin A
(3R,5R)-3-amino-N-(3-amino-3-iminopropyl)-6-[[(2E,4Z)-hexa-2,4-dienoyl]amino]-5-hydroxyhexanamide dihydrochloride
L-threo-Hexonamide,3-amino-N-(3-amino-3-iminopropyl)-6-((1-oxo-2,4-hexadienyl)amino)-2,3,4,6-tetradeoxy-,(E,Z)-,dihydrochloride

Biological Activity

[Description]:

Sperabillin A (dihydrochloride)is new inhibitors ofglutathione S-transferaseisolated from the culture broth ofStreptomyces sp[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Gutathione S-transferase

[References]

[1]. Aoyama T, et al. Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. II. Structure determination of benastatins A and B [published correction appears in J Antibiot (Tokyo) 1992 Nov;45(11):C6-7]. J Antibiot (Tokyo). 1992;45(9):1391-1396.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H29Cl2N5O3

[ Molecular Weight ]:
398.32800

[ Exact Mass ]:
397.16500

[ PSA ]:
161.30000

[ LogP ]:
3.93050

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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