Naxagolide Hydrochloride

Names

[ Name ]:
Naxagolide Hydrochloride

[Synonym ]:
(-)-PHNO
Dopazinol Hydrochloride
(+)-Propyl-9-hydroxynaphthoxazine Hydrochloride
R(+)-PHNO
trans-N-n-propyl-9-hydroxy-2,3,4a,5,6,10b-hexahydro-4H-naphth[1,2b][1,4]oxazine
(+)-PHNO Hydrochloride
MK 458
Nazagolide HCl

Biological Activity

[Description]:

Naxagolide hydrochloride is an agonist of D2. Naxagolide hydrochloride can be used in study Parkinsonism[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Cutler NR, et al. Pharmacokinetics and dose proportionality of D2-agonist MK-458 (HPMC) in parkinsonism. Clin Pharmacokinet. 1992 Mar;22(3):223-30.

Chemical & Physical Properties

[ Density]:
1.109g/cm3

[ Boiling Point ]:
391.7ºC at 760mmHg

[ Melting Point ]:
273-275ºC (dec.)

[ Molecular Formula ]:
C₁₅H₂₂ClNO₂

[ Molecular Weight ]:
283.79400

[ Flash Point ]:
190.7ºC

[ Exact Mass ]:
283.13400

[ PSA ]:
32.70000

[ LogP ]:
3.23020

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.