SALANNIN(P)

Names

[ CAS No. ]:
992-20-1

[ Name ]:
SALANNIN(P)

[Synonym ]:
SALANNIN(P)
Salannin

Biological Activity

[Description]:

Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vivo]

Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions[2]. Animal Model: Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions)[2] Dosage: 10, 20 and 50 mg/kg Administration: P.o. Result: Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions.

[References]

[1]. Divakar C. Madhu, et al. NTIULCER. ANTIBACTERIAL AND SPERMICIDAL ACTIVITIES OF SALANNIN.

[2]. Mohammad Asif, et al. A Review on Spermicidal Activities of Azadirachta indica. Journal of Pharmacognosy and Phytochemistry.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₄₄O₉

[ Molecular Weight ]:
596.70800

[ Exact Mass ]:
596.29900

[ PSA ]:
110.50000

[ LogP ]:
5.29100

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.