<Suppliers Price>

Tricarballylic acid

Names

[ CAS No. ]:
99-14-9

[ Name ]:
Tricarballylic acid

[Synonym ]:
EINECS 202-733-3
Propane 1,2,3-tricarboxylic acid
3-Carboxyglutaric acid
Carballylic acid
tricarballylic acid
3-Carboxypentane-1,5-dioic acid
MFCD00002723
Propane-1,2,3-tricarboxylic acid
QV1YVQ1VQ
1,2,3-Propanetricarboxylic acid
β-Carboxyglutaric acid

Biological Activity

[Description]:

Tricarballylic acid, a conjugate acid of a tricarballylate, is a competitive inhibitor of the enzyme aconitate hydratase (aconitase; EC 4.2.1.3) with a Ki value of 0.52 mM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

Ki: 0.52 mM (aconitate hydratase)[1]


[References]

[1]. Russell, James B.; Forsberg, Neil (2007). "Production of tricarballylic acid by rumen microorganisms and its potential toxicity in ruminant tissue metabolism". British Journal of Nutrition. 56 (1): 153–62. 

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
266.4±20.0 °C at 760 mmHg

[ Melting Point ]:
156-161 °C(lit.)

[ Molecular Formula ]:
C6H8O6

[ Molecular Weight ]:
176.124

[ Flash Point ]:
129.2±18.3 °C

[ Exact Mass ]:
176.032089

[ PSA ]:
111.90000

[ LogP ]:
-1.33

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.529

[ Water Solubility ]:
H2O: 50 mg/mL, clear

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2917190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Enhanced shRNA delivery and ABCG2 silencing by charge-reversible layered nanocarriers.

Small 11(8) , 952-62, (2015)

Polycationic vectors have been used to deliver short hairpin RNAs (shRNAs) to knock-down genes for cancer therapies, but their inefficiency in lysosomal escape and shRNA release causes their low gene ...

Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses.

Clin. Exp. Immunol. 180 , 520-30, (2015)

Citrate, a central component of cellular metabolism, is a widely used anti-coagulant due to its ability to chelate calcium. Adenosine triphosphate (ATP)-citrate lyase, which metabolizes citrate, has b...

Reactions of atomic metal anions in the gas phase: competition between electron transfer, proton abstraction and bond activation.

J. Phys. Chem. A 115(48) , 14006-12, (2011)

Bare metal anions K(-), Rb(-), Cs(-), Fe(-), Co(-), Ni(-), Cu(-), and Ag(-), generated by electrospray ionization of the corresponding oxalate or tricarballylate solutions, were allowed to react with ...


More Articles


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.