3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol

Names

[ Name ]:
3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol

[Synonym ]:
(3β,6α,12β,20E)-Dammar-20(22)-ene-3,6,12,25-tetrol
Dammar-20(22)-ene-3,6,12,25-tetrol, (3β,6α,12β,20E)-

Biological Activity

[Description]:

3β,6α,12β-Dammar-E-20(22)-ene-3,6,12,25-tetraol, a SIRT1 activator, exhibits significant stimulation of SIRT1 activity. Anti-tumor activity[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

[Target]

SIRT1

[References]

[1]. Xiu-Wei Yang, et al. SIRT1 activator isolated from artificial gastric juice incubate of total saponins in stems and leaves of Panax ginseng. Bioorg Med Chem Lett. 2018 Feb 1;28(3):240-243.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
589.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₅₂O₄

[ Molecular Weight ]:
476.732

[ Flash Point ]:
240.1±24.7 °C

[ Exact Mass ]:
476.386566

[ LogP ]:
5.62

[ Vapour Pressure ]:
0.0±3.8 mmHg at 25°C

[ Index of Refraction ]:
1.540

Related Compounds

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