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VIP (guinea pig) trifluoroacetate salt

Names

[ CAS No. ]:
96886-24-7

[ Name ]:
VIP (guinea pig) trifluoroacetate salt

[Synonym ]:
M.W. 3344.86 C147H239N43O42S2
L-His-L-Ser-L-Asp-L-Ala-L-Leu-L-Phe-L-Thr-L-Asp-L-Thr-L-Tyr-L-Thr-L-Arg-L-Leu-L-Arg-L-Lys-L-Gln-L-Met-L-Ala-L-Met-L-Lys-L-Lys-L-Tyr-L-Leu-L-Asn-L-Ser-L-Val-L-Leu-L-Asn-NH2
H-His-Ser-Asp-Ala-Leu-Phe-Thr-Asp-Thr-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Met-Lys-Lys-Tyr-Leu-Asn-Ser-Val-Leu-Asn-NH2
HIS-SER-ASP-ALA-LEU-PHE-THR-ASP-THR-TYR-THR-ARG-LEU-ARG-LYS-GLN-MET-ALA-MET-LYS-LYS-TYR-LEU-ASN-SER-VAL-LEU-ASN-NH2
HIS-SER-ASP-ALA-VAL-PHE-THR-ASP-ASN-TYR-THR-ARG: HSDAVFTDNYTR
VIP

Biological Activity

[Description]:

VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease
Research Areas >> Neurological Disease

[In Vitro]

Vasoactive intestinal peptide (10(-7)M) shortened S phase and G1 phase of neuroepithelial cells by 50% (4.8-2.4 h) and 58% (1.9-0.8 h), respectively, compared with controls[1].

[References]

[1]. P Gressens, et al. Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos. Eur J Neurosci. 1998 May;10(5):1734-42.

[2]. M G Bryant, et al. Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet. 1976 May 8;1(7967):991-3.

Chemical & Physical Properties

[ Molecular Formula ]:
C147H239N43O42S2

[ Molecular Weight ]:
3344.86000

[ Exact Mass ]:
3342.73000

[ PSA ]:
1481.43000

[ LogP ]:
3.92490

Related Compounds