Levomilnacipran

Names

[ Name ]:
Levomilnacipran

Biological Activity

[Description]:

Dextromilnacipran (F2696; (1R,2S)-milnacipran), an enantiomer of milnacipran, is a selective serotonin and norepinephrine (5-HT/NE) reuptake inhibitor. Dextromilnacipran also is a human alpha-adrenergic receptor antagonist, with an IC50 of 3.4 μM. (patent WO2013014263A1).

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

[Target]

IC50: 3.4 μM (alpha-adrenergic receptor)

[References]

[1]. Pierre Sokoloff. Levomilnacipran drug for functional rehabilitation after an acute neurological stroke. WO2013014263A1.

Chemical & Physical Properties

[ Density]:
1.077

[ Boiling Point ]:
393ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂N₂O

[ Molecular Weight ]:
246.34800

[ Exact Mass ]:
246.17300

[ PSA ]:
46.33000

[ LogP ]:
2.47170

Related Compounds

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