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Forxiga

Names

[ CAS No. ]:
960404-48-2

[ Name ]:
Forxiga

[Synonym ]:
1,2-Propanediol, (2S)-, compd. with D-glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, hydrate (1:1:1)
Dapagliflozin S-propylene glycol monohydrate
dapagliflozin propanediol monohydrate
(2S)-1,2-Propanediol - (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol hydrate (1:1:1)
Dapagliflozin propylene glycolate hydrate
BMS-512148-05
dapagliflozin propylene glycol hydrate
UNII-887K2391VH
Dapagliflozin (S)-Propylene Glycol Hydrate
Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Biological Activity

[Description]:

Dapagliflozin (2S)-1,2-propanediol, hydrate is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin inhibits sodium/glucose cotransporter 2 (SGLT2), which results in excretion of glucose into the urine.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT
Research Areas >> Metabolic Disease

[Related Small Molecules]

Phlorizin | Phloretin | LX-4211 | Ertugliflozin | Licogliflozin | Tofogliflozin (hydrate) | Bexagliflozin | Ipragliflozin | Velagliflozin

Chemical & Physical Properties

[ Molecular Formula ]:
C24H35ClO9

[ Molecular Weight ]:
502.982

[ Exact Mass ]:
502.196960

[ PSA ]:
149.07000

[ LogP ]:
1.13960

Related Compounds