Myristoyl Tetrapeptide-12

Names

[ Name ]:
Myristoyl Tetrapeptide-12

[Synonym ]:
N2-Tetradecanoyl-L-lysyl-L-alanyl-L-lysyl-L-alaninamide
L-Alaninamide, N2-(1-oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-
Myristoyl Tetrapeptide-12

Biological Activity

[Description]:

Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes[1][2].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad

Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad

Research Areas >> Metabolic Disease

[References]

[1]. Haeyoung Kwon, et al. Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide. Cell Biochem Funct. 2014 Dec;32(8):665-74.

[2]. C. Diehl. Peptides in cosmeceuticals. ISSN 1727-5741 (Print), ISSN 2522-1035 (Online).

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
932.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₂H₆₃N₇O₅

[ Molecular Weight ]:
625.886

[ Flash Point ]:
517.6±34.3 °C

[ Exact Mass ]:
625.489075

[ LogP ]:
3.11

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.506

Related Compounds

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