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(S)-Citalopram N-Oxide

Names

[ CAS No. ]:
959119-22-3

[ Name ]:
(S)-Citalopram N-Oxide

Biological Activity

[Description]:

Clarithromycin-d3is the deuterium labeledClarithromycin(HY-17508)[1]. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM[3]. Clarithromycin significantly inhibits the HERG potassium current[4].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K[5].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Melting Point ]:
>136°C (dec.)

[ Molecular Formula ]:
C38H66D3NO13

[ Molecular Weight ]:
750.97

[ Appearance of Characters ]:
Solid | White to Off-White

[ Storage condition ]:
-20°C Freezer, Under inert atmosphere

[ Stability ]:
Hygroscopic

[ Water Solubility ]:
Chloroform (Slightly), Methanol (Slightly)

Safety Information

[ HS Code ]:
9999999999


Related Compounds

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