Momordin II

Names

[ Name ]:
Momordin II

[Synonym ]:
Hemsloside Ma 1
3-O-α-L-Arabinopyranosyl-(1→3)-β-D-glucuronopyranosyloleanolic acid 28-O-α-D-glucopyranoside
(+)-Momordin II
Momordin II

Biological Activity

[Description]:

Momordin II, an oleanane-type triterpene glycoside, is a ribosome inactivating protein. Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. M Ortigao, et al. Momordin II, a ribosome inactivating protein from Momordica balsamina, is homologous to other plant proteins. Nucleic Acids Res

[2]. P Valbonesi, et al. Preparation of highly purified momordin II without ribonuclease activity. Life Sci. 1999;65(14):1485-91.

[3]. Hung-Tse Huang, et al. Anti-Inflammatory and anti-proliferative oleanane-type triterpene glycosides from the vine of Momordica cochinchinensis. Nat Prod Res. 2021 Aug;35(16):2707-2714.

Chemical & Physical Properties

[ Density]:
1.42±0.1 g/cm3 (20 °C, 760 mmHg)

[ Boiling Point ]:
996.5±65.0 °C (760 mmHg)

[ Molecular Formula ]:
C₄₇H₇₄O₁₈

[ Molecular Weight ]:
927.08000

[ Flash Point ]:
284.787°C

[ Exact Mass ]:
926.48800

[ PSA ]:
291.82000

[ LogP ]:
0.87190

Precursor & DownStream

Precursor

DownStream

Related Compounds

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