4-(2,2,3-Trimethylcyclopentyl)butanoic acid

Names

[ Name ]:
4-(2,2,3-Trimethylcyclopentyl)butanoic acid

[Synonym ]:
4-(2,2,3-Trimethylcyclopentyl)butanoic acid
Cyclopentanebutanoic acid, 2,2,3-trimethyl-

Biological Activity

[Description]:

GIV3727 is a bitter taste receptor hTAS2R antagonist, which can inhibit the activation of hTAS2R31 by saccharin and acesulfame potassium, and can effectively reduce the bitter quality of food, beverage and medicine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Jay P Slack, et al. Modulation of bitter taste perception by a small molecule hTAS2R antagonist. Curr Biol. 2010 Jun 22;20(12):1104-9.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
289.3±8.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₂₂O₂

[ Molecular Weight ]:
198.30

[ Flash Point ]:
132.6±9.8 °C

[ Exact Mass ]:
198.161987

[ PSA ]:
37.30000

[ LogP ]:
4.33

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.452

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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