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LIN28 inhibitor LI71 enantiomer

Names

[ CAS No. ]:
956189-58-5

[ Name ]:
LIN28 inhibitor LI71 enantiomer

[Synonym ]:
MFCD07403664

Biological Activity

[Description]:

LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

LIN280[1]


[References]

[1]. Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018;23(10):3091-3101.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21NO3

[ Molecular Weight ]:
335.40

[ Storage condition ]:
-20°C

Related Compounds