LJP 1586

Names

[ Name ]:
LJP 1586

[Synonym ]:
(2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1)
Benzenepropanamine, β-(fluoromethylene)-4-methoxy-, (βZ)-, hydrochloride (1:1)

Biological Activity

[Description]:

LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324(2):867-75.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅ClFNO

[ Molecular Weight ]:
231.69

[ Exact Mass ]:
231.082626

Related Compounds

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