955037-42-0

955037-42-0 structure

Name: LJP 1586
Chemical Name: (2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1)
CAS Number: 955037-42-0
Molecular Formula: C₁₁H₁₅ClFNO
Molecular Weight: 231.69
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-07-15 00:12:36
Modify Date: 2025-08-25 11:51:31
LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].

Name	(2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1)
Synonyms	(2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1) Benzenepropanamine, β-(fluoromethylene)-4-methoxy-, (βZ)-, hydrochloride (1:1)

Description	LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324(2):867-75.