3,4,5-Trimethoxyphenylacetic acid

Names

[ CAS No. ]:
951-82-6

[ Name ]:
3,4,5-Trimethoxyphenylacetic acid

[Synonym ]:
EINECS 213-456-2
3,4,5-Trimethoxyphenylacetic acid
(3,4,5-Trimethoxyphenyl)acetic acid
2-(3,4,5-trimethoxyphenyl)acetic acid
MFCD00004336
Benzeneacetic acid, 3,4,5-trimethoxy-

Biological Activity

[Description]:

3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Demisch L, et al. 3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans. Drug Metab Dispos. 1978 Sep-Oct;6(5):507-9.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
360.8±37.0 °C at 760 mmHg

[ Melting Point ]:
117-120 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₄O₅

[ Molecular Weight ]:
226.226

[ Flash Point ]:
138.1±20.0 °C

[ Exact Mass ]:
226.084122

[ PSA ]:
64.99000

[ LogP ]:
0.94

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.520

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29189090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Bacterial degradation of 3,4,5-trimethoxyphenylacetic and 3-ketoglutaric acids.

J. Bacteriol. 147(2) , 477-81, (1981)

When grown at the expense of 3,4,5-trimethoxyphenylacetic acid, a species of Arthrobacter readily oxidized 3,4-dihydroxy-5-methoxyphenylacetic acid, but other structurally related aromatic acids were ...