TTP-8307
Names
[ CAS No. ]:
950225-08-8
[ Name ]:
TTP-8307
Biological Activity
[Description]:
TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.
[References]
References 1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. 2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72. 3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18. View Related Products by Target Enterovirus
Chemical & Physical Properties
[ Molecular Formula ]:
C27H21FN4O
[ Molecular Weight ]:
436.49
Related Compounds
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