9-Aminophenanthrene
Names
[ CAS No. ]:
947-73-9
[ Name ]:
9-Aminophenanthrene
[Synonym ]:
EINECS 213-431-6
Phenanthren-9-ylaMine
9-aminophenantrene
9-Phenanthrylamine
9-PHENANTHRENAMINE
2-aminophenanthrene
9-AMINOPHENANTHRENE
Phenanthrylamine
MFCD00001177
Chemical & Physical Properties
[ Density]:
1.208g/cm3
[ Boiling Point ]:
408.2ºC at 760mmHg
[ Melting Point ]:
137-139ºC(lit.)
[ Molecular Formula ]:
C14H11N
[ Molecular Weight ]:
193.24400
[ Flash Point ]:
224.4ºC
[ Exact Mass ]:
193.08900
[ PSA ]:
26.02000
[ LogP ]:
4.15640
[ Index of Refraction ]:
1.765
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SG0175000
- CHEMICAL NAME :
- 9-Phenanthrylamine
- CAS REGISTRY NUMBER :
- 947-73-9
- BEILSTEIN REFERENCE NO. :
- 2209422
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C14-H11-N
- MOLECULAR WEIGHT :
- 193.26
- WISWESSER LINE NOTATION :
- L B666J HZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg/6D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 250 ng/plate
- REFERENCE :
- JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,293,1983
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26;S37/S39
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
SG0175000
[ HS Code ]:
2921499090
Synthetic Route
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Drug Metab. Rev. 36(2) , 219-30, (2004)
Cytochrome P450-dependent drug metabolism in vitro frequently deviates from simple Michaelis-Menten kinetic models, and demonstrates both positive and negative homotropic and heterotropic effects. The...
Fluorometric high-performance liquid chromatography of 9-aminophenanthrene-derivatized free fatty acids.J. Chromatogr. A. 305(2) , 261-70, (1984)
The application of 9-aminophenanthrene (9-AP), a fluorescence-labeling reagent for free fatty acids (FFA), was examined. 9-AP dissolved in benzene was added to a benzene solution of FFA chlorides deri...
HPLC on Chiralcel OJ-R for enantiomer separation and analysis of ketoprofen, from horse plasma, as the 9-aminophenanthrene derivative.J. Pharm. Pharmacol. 50(3) , 291-6, (1998)
Racemic ketoprofen is a non-steroidal anti-inflammatory drug used to treat musculoskeletal and colic conditions in horses. The enantioselective chiral inversion of ketoprofen administered to horses ha...