2-(Trifluoromethoxy)benzaldehyde

Names

[ Name ]:
2-(Trifluoromethoxy)benzaldehyde

[Synonym ]:
Benzaldehyde, 2-(trifluoromethoxy)-
2-(Trifluoromethoxy) benzaldehyde
α,α,α-Trifluoro-o-anisaldehyde
MFCD00042405
2-(Trifluormethoxy)benzolcarbaldehyd
2-(Trifluoromethoxy)benzaldehyde
VHR BOXFFF

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
187.5±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₅F₃O₂

[ Molecular Weight ]:
190.119

[ Flash Point ]:
65.7±20.8 °C

[ Exact Mass ]:
190.024170

[ PSA ]:
26.30000

[ LogP ]:
2.75

[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.479

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NA 1993 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

Trifluoromethoxy substituted anilines: metalation as the key step for structural elaboration.

J. Org. Chem. 68(12) , 4693-9, (2003)

Trifluoromethoxy-substituted anilines undergo hydrogen/lithium permutation ("metalation") with optional site selectivity depending on the N-protective group employed. N-tert-Butoxycarbonyl-2- and -4-(...