BAL-30072

Names

[ Name ]:
BAL-30072

[Synonym ]:
ly97zjm4qx
unii-ly97zjm4qx

Biological Activity

[Description]:

BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC90: 4 μg/mL (MDR Acinetobacter spp.), 8 μg/mL (MDR P. aeruginosa)[1][2].

[References]

[1]. Page MG, et al. In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli. Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302.

[2]. Michael Hornsey, et al. In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. Int J Antimicrob Agents. 2013 Oct;42(4):343-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₈N₆O₁₀S₂

[ Molecular Weight ]:
518.47800

[ Exact Mass ]:
518.05300

[ PSA ]:
276.81000

[ LogP ]:
0.37990

Related Compounds

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