Ceftolozane sulfate

Names

[ CAS No. ]:
936111-69-2

[ Name ]:
Ceftolozane sulfate

Biological Activity

[Description]:

Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. Ceftolozane sulfate inhibits P. aeruginosa PAO1 with an MIC of 0.5 μg/mL. Ceftolozane sulfate can also inhibit β-lactam-resistant P. aeruginosa[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC: 0.5 μg/mL (P. aeruginosa PAO1)[1]


[References]

[1]. Moyá B, et al. Affinity of the new cephalosporin CXA-101 to penicillin-binding proteins of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2010 Sep;54(9):3933-7.  

[2]. Moya B, et al. Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients. Antimicrob Agents Chemother. 2010 Mar;54(3):1213-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C23H32N12O12S3

[ Molecular Weight ]:
764.77

Related Compounds

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