MK-1832

Names

[ Name ]:
MK-1832

Biological Activity

[Description]:

MK-1832 is a potent, selective Kv1.5 inhibitor with IC50 of 86 nM, exhibits improved selectivity for IKur over IKs (>3000-fold) compares with MK-0448 (70-fold), also exhibits an improved preclinical pharmacokinetic profile.

[References]

References 1. Wolkenberg SE, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1062-1069. View Related Products by Target Potassium Channel

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₇Cl₂N₃O

[ Molecular Weight ]:
422.309

Related Compounds

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