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3-Methoxycatechol

Names

[ CAS No. ]:
934-00-9

[ Name ]:
3-Methoxycatechol

[Synonym ]:
3-Methoxy-1,2-benzenediol
3-Methoxybenzene-1,2-diol
MFCD00002191
EINECS 213-276-4
1,2-Benzenediol, 3-methoxy-
3-Methoxycatechol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
268.1±0.0 °C at 760 mmHg

[ Melting Point ]:
38-43 °C(lit.)

[ Molecular Formula ]:
C7H8O3

[ Molecular Weight ]:
140.137

[ Flash Point ]:
119.5±21.8 °C

[ Exact Mass ]:
140.047348

[ PSA ]:
49.69000

[ LogP ]:
0.70

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.580

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ9002750
CHEMICAL NAME :
1,2-Benzenediol, 3-methoxy-
CAS REGISTRY NUMBER :
934-00-9
LAST UPDATED :
199606
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-O3
MOLECULAR WEIGHT :
140.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
428 gm/kg/51W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 85,17,1994

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CZ9002750

[ HS Code ]:
2909500000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone.

J. Bacteriol. 186(14) , 4705-13, (2004)

Wild-type toluene 4-monooxygenase (T4MO) of Pseudomonas mendocina KR1 oxidizes toluene to p-cresol (96%) and oxidizes benzene sequentially to phenol, to catechol, and to 1,2,3-trihydroxybenzene. In th...


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