4-Chloro-N-methylaniline

Names

[ CAS No. ]:
932-96-7

[ Name ]:
4-Chloro-N-methylaniline

[Synonym ]:
Aniline,p-chloro-N-methyl-(7CI,8CI)
N-methyl N-4-chlorophenylamine
4-Chloro-N-methylaniline
N-methyl-4-Cl-aniline
BENZENAMINE,4-CHLORO-N-METHYL-
Aniline,p-chloro-N-methyl
MFCD00000614
N-methyl-p-chloroaniline
N-methyl-4-chloroaniline
Benzenamine,4-chloro-N-methyl
N-(P-CHLOROBENZYL)METHYLAMINE
4-chloro-N-methylbenzenamine
4-CHLOR-N-METHYLANILIN
Benzenamine, 4-chloro-N-methyl-
4-chloro-N-methyl-aniline
EINECS 213-262-8
p-chloro-N-methylaniline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
240.8±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₈ClN

[ Molecular Weight ]:
141.598

[ Flash Point ]:
51.7±0.0 °C

[ Exact Mass ]:
141.034531

[ PSA ]:
12.03000

[ LogP ]:
2.38

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CX9857900

CHEMICAL NAME :: Benzenamine, 4-chloro-N-methyl-

CAS REGISTRY NUMBER :: 932-96-7

BEILSTEIN REFERENCE NO. :: 2205846

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H8-Cl-N

MOLECULAR WEIGHT :: 141.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 100 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,183,1988

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H318-H335-H412

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R10;R20/21/22;R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
CX9857900

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

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Fundam. Appl. Toxicol. 6(2) , 190-207, (1986)

Attempts have been made to review the role of pharmacokinetics and metabolism in species and age sensitivity as well as the development of various toxic conditions of some neurotoxic chemicals. The ro...

Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.

Bioorg. Med. Chem. Lett. 20(4) , 1363-7, (2010)

A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were...

FT-IR, FT-Raman, NMR spectra and DFT calculations on 4-chloro-N-methylaniline.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(5) , 1523-9, (2010)

In this work, the vibrational spectral analysis was carried out by using FT-IR and FT-Raman spectroscopy in the range 400-4000 and 50-3500cm(-1) respectively, for the title molecule. The structural an...