DHFR-IN-10

Names

[ CAS No. ]:
929484-47-9

[ Name ]:
DHFR-IN-10

Biological Activity

[Description]:

DHFR-IN-10 (compound 4c) is a potent DHFR inhibitor, with an IC50 of 4.21 μM for M. tuberculosis DHFR enzyme. DHFR-IN-10 exhibits potent antituberculosis efficiency[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Dawood DH, et, al. New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies. ACS Omega. 2023 Oct 13;8(42):39250-39268.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H14BrN3S3

[ Molecular Weight ]:
472.44

Related Compounds

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