HG106

Names

[ Name ]:
HG106

Biological Activity

[Description]:

HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₃ClN₄O₂

[ Molecular Weight ]:
316.74

Related Compounds

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