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928712-10-1

928712-10-1 structure
928712-10-1 structure
  • Name: HG106
  • Chemical Name: Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-
  • CAS Number: 928712-10-1
  • Molecular Formula: C15H13ClN4O2
  • Molecular Weight: 316.74
  • Catalog: Research Areas Cancer
  • Create Date: 2022-03-13 14:29:57
  • Modify Date: 2025-10-13 17:54:47
  • HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].

Name Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-
Description HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].
Related Catalog
References

[1]. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.  

Molecular Formula C15H13ClN4O2
Molecular Weight 316.74
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