Ethanolamine-O-sulfate
Names
[ CAS No. ]:
926-39-6
[ Name ]:
Ethanolamine-O-sulfate
[Synonym ]:
2-Aminoethyl hydrogen sulfate
2-aminoethyl hydrogen sulphate
Ethanolamine-O-sulfate
Ethanolamine O-sulfate
2-Aminoethyl sulfuric acid
EINECS 213-135-7
MFCD00008179
Ethanol, 2-amino-, hydrogen sulfate (ester)
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Melting Point ]:
277 °C (dec.)(lit.)
[ Molecular Formula ]:
C2H7NO4S
[ Molecular Weight ]:
141.146
[ Exact Mass ]:
141.009583
[ PSA ]:
98.00000
[ LogP ]:
-1.02
[ Index of Refraction ]:
1.511
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KJ6371000
- CHEMICAL NAME :
- Ethanol, 2-amino-, hydrogen sulfate (ester)
- CAS REGISTRY NUMBER :
- 926-39-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C2-H7-N-O4-S
- MOLECULAR WEIGHT :
- 141.16
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - excitement
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 33(10),57,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Skin and Appendages - hair
- REFERENCE :
- NEPHBW Neuropharmacology. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.9- 1970- Volume(issue)/page/year: 21,803,1982
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
KJ6371000
[ HS Code ]:
2922199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Anal. Bioanal. Chem 386(3) , 666-74, (2006)
Characterizing the biological effects of metabolic transformations (or biotransformation) is one of the key steps in developing safe and effective pharmaceuticals. Sulfate conjugation, one of the majo...
The effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl-GABA and ethanolamine-O-sulphate on the in vivo release of GABA from rat hippocampus.J. Neurochem. 64 , 2256, (1995)
The effects of chronic treatment with the specific, mechanism-based, irreversible inhibitors of 4-aminobutyrate aminotransferase (EC 2.6.1.19; GABA transaminase), ethanolamine O-sulphate (EOS), and 4-...
GABA-mimetic compounds block haloperidol-induced hyperprolactinemia in rats.Adv. Biochem. Psychopharmacol. 42 , 139-44, (1986)