1,3,2-Dioxathiolane 2,2-dioxide

Names

[ Name ]:
1,3,2-Dioxathiolane 2,2-dioxide

[Synonym ]:
1,3,2-Dioxathiolane 2,2-dioxide
1,3,2-Dioxathiolane-2,2-dioxide
ETHYLENESULFATE
Ethylene Sulfate
MFCD00221769
1,3,2-Dioxathiolane, 2,2-dioxide

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
231.1±7.0 °C at 760 mmHg

[ Melting Point ]:
95-97ºC(lit.)

[ Molecular Formula ]:
C₂H₄O₄S

[ Molecular Weight ]:
124.116

[ Flash Point ]:
93.5±18.2 °C

[ Exact Mass ]:
123.983032

[ PSA ]:
60.98000

[ LogP ]:
-0.14

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.469

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JH4800000

CHEMICAL NAME :: 1,3,2-Dioxathiolane, 2,2-dioxide

CAS REGISTRY NUMBER :: 1072-53-3

BEILSTEIN REFERENCE NO. :: 1237731

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C2-H4-O4-S

MOLECULAR WEIGHT :: 124.12

WISWESSER LINE NOTATION :: T5OSWOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 128 mg/kg/64W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 840 mg/kg/42W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Host-mediated assay

TEST SYSTEM :: Rodent - mouse Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 mmol/kg

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 19,241,1977

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
JH4800000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Computational Study of Ring Strain in 1, 3, 2-Dioxathiolane, its 2-Oxide and its 2, 2-Dioxide. Petersenb KN and Skanckeb PN.

Acta Chem. Scand. 53 , 1003-1008, (1999)

1, 3, 2-Dioxathiolane 2, 2-Dioxide. Lynch NJ, et al.

e-EROS Encyclopedia of Reagents for Organic Synthesis. , (2009)