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m-PEG-NHS ester (MW 1000)

Names

[ CAS No. ]:
92451-01-9

[ Name ]:
m-PEG-NHS ester (MW 1000)

[Synonym ]:
(2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate,2-methoxyethanol

Biological Activity

[Description]:

m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3(2): 123-129.

Chemical & Physical Properties

[ Molecular Formula ]:
(C2H4O)nC7H9NO5

[ Molecular Weight ]:
1000(Average)

[ Exact Mass ]:
293.11100

[ PSA ]:
122.60000

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3