VU534

Names

[ Name ]:
VU534

Biological Activity

[Description]:

VU534 is a NAPE-PLD activator, with an EC50 of 0.30 μM. VU534 is dual inhibitors of FAAH and sEH (IC50 of 1.2 μM). VU534 increases efferocytosis in a NAPE-PLD dependent manner. VU534 has the potential for cardiometabolic diseases study [1] .

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH

Signaling Pathways >> Neuronal Signaling >> FAAH

[Target]

NAPE-PLD activator, with an EC50 of 0.30 μM

[References]

[1]. Jonah E Zarrow, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem. Biol. 2023, 18, 8, 1891–1904.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂FN₃O₃S₂

[ Molecular Weight ]:
447.55

Related Compounds

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