VU533

Names

[ Name ]:
VU533

Biological Activity

[Description]:

APE-PLD (VU533) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM. NAPE-PLD activator (VU533) can enhance NAPE-PLD activity and increase efferocytosis by macrophages. NAPE-PLD activator (VU533) can be used for cardiometabolic diseases research[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase

Research Areas >> Metabolic Disease

[Target]

PLD1:0.3 μM (EC50)

[References]

[1]. Zarrow JE, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem Biol. 2023 Aug 18;18(8):1891-1904.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂FN₃O₃S₂

[ Molecular Weight ]:
447.55

Related Compounds

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