923417-09-8

923417-09-8 structure

Name: VU533
Chemical Name: VU533
CAS Number: 923417-09-8
Molecular Formula: C₂₁H₂₂FN₃O₃S₂
Molecular Weight: 447.55
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
Create Date: 2023-10-25 07:34:24
Modify Date: 2025-08-25 19:26:19
APE-PLD (VU533) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM. NAPE-PLD activator (VU533) can enhance NAPE-PLD activity and increase efferocytosis by macrophages. NAPE-PLD activator (VU533) can be used for cardiometabolic diseases research[1].

Name	VU533

Description	APE-PLD (VU533) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM. NAPE-PLD activator (VU533) can enhance NAPE-PLD activity and increase efferocytosis by macrophages. NAPE-PLD activator (VU533) can be used for cardiometabolic diseases research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Metabolic Disease
Target	PLD1:0.3 μM (EC50)
References	[1]. Zarrow JE, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem Biol. 2023 Aug 18;18(8):1891-1904.

Molecular Formula	C₂₁H₂₂FN₃O₃S₂
Molecular Weight	447.55