Obafluorin

Names

[ Name ]:
Obafluorin

[Synonym ]:
Obafluorin

Biological Activity

[Description]:

Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Scott TA, et al. Immunity-Guided Identification of Threonyl-tRNA Synthetase as the Molecular Target of Obafluorin, a β-Lactone Antibiotic. ACS Chem Biol. 2019 Dec 20;14(12):2663-2671.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄N₂O₇

[ Molecular Weight ]:
358.30200

[ Exact Mass ]:
358.08000

[ PSA ]:
145.17000

[ LogP ]:
2.37050

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.