BTA-EG4

Names

[ Name ]:
BTA-EG4

[Synonym ]:
2-(4-Methylaminophenyl)benzothiazole
2-(4'-methylaminophenyl)benzothiazole
Benzenamine, 4-(2-benzothiazolyl)-N-methyl-
MFCD04974146
4-(1,3-Benzothiazol-2-yl)-N-methylaniline
BTA-1

Biological Activity

[Description]:

BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance the neurotoxicity of amyloid peptides in catalase-overexpressing neuronal cells, and can be used in the study of neurodegenerative diseases[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Amrutha Chilumuri, et al. Benzothiazole Aniline Tetra(ethylene glycol) and 3-Amino-1,2,4-triazole Inhibit Neuroprotection against Amyloid Peptides by Catalase Overexpression in Vitro.Amrutha Chilumuri, Mark Odell, and Nathaniel G. N. Milton.ACS Chemical Neuroscience 2013 4 (11), 1501-1512.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
415.5±47.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₈N₂O₄S

[ Molecular Weight ]:
416.53

[ Flash Point ]:
205.1±29.3 °C

[ Exact Mass ]:
240.072113

[ LogP ]:
4.07

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.712

Related Compounds

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