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TTA-P1

Names

[ CAS No. ]:
918333-06-9

[ Name ]:
TTA-P1

Biological Activity

[Description]:

TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Neurological Disease

[References]

[1]. Uebele VN, Nuss CE, Fox SV, et al. Positive allosteric interaction of structurally diverse T-type calcium channel antagonists. Cell Biochem Biophys. 2009;55(2):81-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H27Cl2FN2O

[ Molecular Weight ]:
389.33500

[ Exact Mass ]:
388.14800

[ PSA ]:
35.83000

[ LogP ]:
5.33210

Related Compounds