5-TAMRA

Names

[ Name ]:
5-TAMRA

[Synonym ]:
3-carboxy-4-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]benzoate
Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt
2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate
5-TAMRA

Biological Activity

[Description]:

The amine-reactive 5-TAMRA, SE and its conjugates yield bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₂N₂O₅

[ Molecular Weight ]:
430.453

[ Exact Mass ]:
430.152863

[ PSA ]:
97.05000

[ LogP ]:
3.72780

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity.

Mol. Cell. Biol. 35 , 3284-300, (2015)

The transcription factor STAT3 is constitutively active in many cancers, where it mediates important biological effects, including cell proliferation, differentiation, survival, and angiogenesis. The ...

Inhibition of N-Methyl-D-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane Potential.

J. Biol. Chem. 290(36) , 22030-48, (2015)

It is widely accepted that overactivation of NMDA receptors, resulting in calcium overload and consequent mitochondrial dysfunction in retinal ganglion neurons, plays a significant role in promoting n...

A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells.

Cell Cycle 13(16) , 2542-53, (2014)

Melanoma has the highest mortality rate of all skin cancers and a major cause of treatment failure is drug resistance. Tumors heterogeneity requires novel therapeutic strategies and new drugs targetin...

Related Compounds

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