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N-Methylpiperazine--d8

Names

[ CAS No. ]:
917358-65-7

[ Name ]:
N-Methylpiperazine--d8

[Synonym ]:
n-methylpiperazine--d8

Biological Activity

[Description]:

1-Methylpiperazine-2,2,3,3,5,5,6,6-d8 is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d8[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Melting Point ]:
216-218°C

[ Molecular Formula ]:
C5H4D8N2

[ Molecular Weight ]:
108.21100

[ Exact Mass ]:
108.15000

[ PSA ]:
15.27000

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H312-H314-H331

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ RIDADR ]:
UN 2734PSN1 3(8) / PGII


Related Compounds