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SP-420

Names

[ CAS No. ]:
911714-45-9

[ Name ]:
SP-420

[Synonym ]:
(4S)-2-{2-Hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl}-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
4-Thiazolecarboxylic acid, 4,5-dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-, (4S)-
SP-420

Biological Activity

[Description]:

SP-420 is a desferrithiocin analogue with iron-clearing efficiency with ICE value of 26.7; more potent than desferrithiocin.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[References]

[1]. Bergeron RJ, et al. Substituent effects on desferrithiocin and desferrithiocin analogue iron-clearing and toxicity profiles. J Med Chem. 2012 Aug 23;55(16):7090-103.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
562.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H21NO6S

[ Molecular Weight ]:
355.406

[ Flash Point ]:
293.8±32.9 °C

[ Exact Mass ]:
355.108948

[ PSA ]:
122.88000

[ LogP ]:
-0.07

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.580

[ Storage condition ]:
2-8℃

Related Compounds

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