SID-852843

Names

[ CAS No. ]:
909859-19-4

[ Name ]:
SID-852843

[Synonym ]:
Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester
HMS2355F20

Biological Activity

[Description]:

SID-852843 is a WNV NS2B-NS3 proteinase inhibitor. SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC50 value of 0.105 μM. SID-852843 can be used for the research of virus infection[1].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

SID-852843 可以抑制 WNV NS2B-NS3 蛋白酶活性 IC50 值为 0.105 μM[1]。

[References]

[1]. Shyama Sidique, et al. Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5773-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C17H15N3O5S

[ Molecular Weight ]:
373.38300

[ Exact Mass ]:
373.07300

[ PSA ]:
121.89000

[ LogP ]:
3.59210

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport


Related Compounds