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KPLH1130

Names

[ CAS No. ]:
906669-07-6

[ Name ]:
KPLH1130

Biological Activity

[Description]:

KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> PDHK
Research Areas >> Inflammation/Immunology

[Target]

PDK[1]


[References]

[1]. Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H13N3O3

[ Molecular Weight ]:
283.28


Related Compounds