KPLH1130

Names

[ Name ]:
KPLH1130

Biological Activity

[Description]:

KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> PDHK

Research Areas >> Inflammation/Immunology

[Target]

PDK[1]

[References]

[1]. Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₃N₃O₃

[ Molecular Weight ]:
283.28

Related Compounds

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