Lysozyme hydrochloride

Names

[ Name ]:
Lysozyme hydrochloride

[Synonym ]:
Muramidase hydrolase
Murazyme
Lysozyme chloride
MFCD00198076
EINECS 232-954-0

Biological Activity

[Description]:

Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema[1][2][3].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Lysozyme 是一种普遍存在的酶。鸡蛋是 Lysozyme 最丰富的来源，约占蛋白蛋白质的 3.4%。Lysozyme 是一种天然抗菌素，可水解细菌细胞壁肽聚糖层中 N-acetylmuramic acid 和 N-acetylglucosamine 之间的 β(1-4) 糖苷连接，导致细胞裂解。Lysozyme chloride 的杀菌作用主要局限于革兰氏阳性细菌，包括病原体，如 Listeria monocytogenes 和某些 Clostridium，以及一些腐败生物，包括嗜热孢子形成细菌和某些酵母。革兰氏阴性菌由于其复杂的细胞壁结构而对 Lysozyme chloride 的作用更有抵抗力[1]。 Lysozyme (1 mg/mL) chloride 降低透明质酸 (HA) 防止弹性蛋白酶损伤弹性纤维的能力[3]。

[In Vivo]

叙利亚仓鼠在给予弹性蛋白酶前暴露于雾化 Lysozyme (20 mg in 20 ml of water; 50 min) chloride 中导致气道扩大显著增加[3]。

[References]

[1]. Banerjee P, et al. Influence of carbon dioxide on the activity of chicken egg white lysozyme. Poult Sci. 2011 Apr;90(4):889-95.

[2]. Jing T, et al. Magnetic molecularly imprinted nanoparticles for recognition of lysozyme. Biosens Bioelectron. 2010 Oct 15;26(2):301-6.

[3]. Cantor JO, et al. The effect of lysozyme on elastase-mediated injury. Exp Biol Med (Maywood). 2002 Feb;227(2):108-13.

Chemical & Physical Properties

[ Storage condition ]:
−20°C

[ Stability ]:
Stable. Store cold. Incompatible with strong oxidizing agents.

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
OL5989850

Articles

Sequential separation of lysozyme, ovomucin, ovotransferrin, and ovalbumin from egg white.

Poult. Sci. 93(4) , 1001-9, (2014)

Ovalbumin, ovotransferrin, ovomucin, and lysozyme are a few of the egg white proteins that can be used as functional components. The objective of this study was to develop a simple, sequential separat...

Refolding of SDS-denatured proteins using amphipathic cosolvents and osmolytes.

Curr. Protoc. Protein Sci. Chapter 28 , Unit28.5, (2013)

Currently, the investigation of protein refolding processes involves several time-consuming stages that require large amounts of protein and costly chemicals. Consequently, there is great interest in ...

Functional display of active tetrameric beta-galactosidase using Bacillus subtilis spore display system.

J. Nanosci. Nanotechnol. 13(3) , 2313-9, (2013)

For the functional bacterial surface display of active enzyme of multimeric form, which is generally impossible due to molecular assembly of the monomer subunit subsequent to the secretion of displaye...