Luxalbendazole

Names

[ Name ]:
Luxalbendazole

[Synonym ]:
2-[(Methoxycarbonyl)amino]-1H-benzimidazol-6-yl 4-fluorobenzenesulfonate
Luxalbendazole
2-((Methoxycarbonyl)amino)-1H-benzimidazol-6-yl 4-Fluorobenzenesulfonate
2-[(methoxycarbonyl)amino]-1h-benzimidazol-6-yl-4-fluorbenzolsulfonat
methyl 5-hydroxy-2-benzimidazolecarbamate p-fluorobenzenesulfonate
LUXABENDAZOLUM
luxabendazole
Benzenesulfonic acid, 4-fluoro-, 2-[(methoxycarbonyl)amino]-1H-benzimidazol-6-yl ester

Biological Activity

[Description]:

Luxabendazole (HOE 216V) is an effective anthelmintic against trematodes, cestodes and nematodes[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. A Criado-Fornelio, et al. Biochemical effects of luxabendazole on Trichinella spiralis. Parasitol Res. 1990;76(6):518-20.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₁₅H₁₂FN₃O₅S

[ Molecular Weight ]:
365.336

[ Exact Mass ]:
365.048157

[ PSA ]:
118.76000

[ LogP ]:
2.67

[ Index of Refraction ]:
1.664

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Activity of luxabendazole against liver flukes, gastrointestinal roundworms, and lungworms in naturally infected sheep.

Parasitol. Res. 75(1) , 14-8, (1988)

The anthelmintic potential of luxabendazole was investigated in sheep harboring mixed naturally acquired helminth infections. Results were assessed by comparing worm counts of the treated groups (seve...

Determination of luxabendazole in biological fluids by high-performance liquid chromatography.

J. Chromatogr. A. 578(2) , 321-6, (1992)

Luxabendazole, a new benzimidazole, is a highly potent broad-spectrum anthelmintic. A high-performance liquid chromatographic method has been developed for its determination in serum and urine samples...

Biochemical effects of luxabendazole on Trichinella spiralis.

Parasitol. Res. 76(6) , 518-20, (1990)

Biochemical changes produced by luxabendazole in muscle-stage Trichinella spiralis larvae consisted of a decrease in free glucose and glycogen levels (46.71% and 35.66%, respectively) after in vivo tr...