SHP 244

Names

[ Name ]:
SHP 244

Biological Activity

[Description]:

SHP244 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 60 uM (SHP2 1-525), equipotent on the double mutant (SHP2T253M/Q257L IC50=68 uM), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM).

[References]

References 1. Fodor M, et al. ACS Chem Biol. 2018 Jan 18. doi: 10.1021/acschembio.7b00980. View Related Products by Target Protein Phosphatase/PTP

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₇ClN₄O₃

[ Molecular Weight ]:
432.864

Related Compounds

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