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Acyl coenzyme A synthetase

Names

[ CAS No. ]:
9013-18-7

[ Name ]:
Acyl coenzyme A synthetase

[Synonym ]:
Fatty acid CoA ligase
Acetamide, N-[4-[[[(1Z)-3-[[[4-(acetylamino)phenyl]sulfonyl]amino]-4-oxo-1(4H)-naphthalenylidene]amino]sulfonyl]phenyl]-
Acyl-CoA ligase
N,N'-[(4-Oxo-3-naphthalenyl-1-ylidene)bis(sulfamoyl-4,1-phenylene)]diacetamide
Fatty acyl CoA synthetase
Hexanoyl-CoA synthetase
Fatty acid thiokinase (long chain)
Acyl-CoA synthase
3-Hydroxyacyl-CoA synthase
Acyl-coenzyme A ligase
Fatty acid thiokinase
Acyl coenzyme A synthetase
Hexanoyl coenzyme A synthetase
Fatty acyl-coenzyme A synthetase
Fatty acyl-CoA ligase
Acyl CoA synthetase
E.C. 6.2.1.3

Biological Activity

[Description]:

Acyl coenzyme A synthetase (ACS), namely acetyl coenzyme A synthetase, is often used in biochemical research. Acyl coenzyme A synthetase can catalyze the activation of fatty acids by coenzyme A through a two-step thioesterification reaction to produce acyl coenzyme A, and then participate in a variety of anabolic and catabolic lipid metabolism pathways, and participate in the TCA cycle in aerobic respiration[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Christine M Roche, et al. Physiological role of Acyl coenzyme A synthetase homologs in lipid metabolism in Neurospora crassa. Eukaryot Cell. 2013 Sep;12(9):1244-57.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H22N4O7S2

[ Appearance of Characters ]:
powder | white

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U. S. A. 105(31) , 10762-7, (2008)

The eukaryotic cell division cycle is characterized by a sequence of orderly and highly regulated events resulting in the duplication and separation of all cellular material into two newly formed daug...

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet. 36 , 40-5, (2004)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone...


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Related Compounds

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