2-Cyanoethyl diisopropylamidochlorophosphite
Names
[ CAS No. ]:
89992-70-1
[ Name ]:
2-Cyanoethyl diisopropylamidochlorophosphite
[Synonym ]:
Phosphoramidochloridous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl ester
2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE
2-cyanoethyl dipropan-2-ylphosphoramidochloridoite
2-Cyanoethyldiisopropylchlorophosphoramidite
2-Cyanoethyl diisopropylphosphoramidochloridoite
2-Cyanoethyl diisopropylamidochlorophosphite
MFCD00011544
3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Chemical & Physical Properties
[ Density]:
1.061 g/mL at 25 °C(lit.)
[ Boiling Point ]:
343.8±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C9H18ClN2OP
[ Molecular Weight ]:
236.679
[ Flash Point ]:
135.8±28.4 °C
[ Exact Mass ]:
236.084534
[ PSA ]:
49.85000
[ LogP ]:
3.46
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.479
[ Storage condition ]:
−20°C
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H250-H314
[ Precautionary Statements ]:
P222-P231-P280-P305 + P351 + P338-P310-P422
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R20/21/22;R29;R34;R5
[ Safety Phrases ]:
S26-S36/37/39-S45-S8
[ RIDADR ]:
UN 2845 4.2/PG 1
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
8
Articles
J. Am. Chem. Soc. 137 , 5629-35, (2015)
Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrit...
Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window.Bioconjug. Chem. 4 , 499, (1993)
Leishmania donovani, a protozoan parasite, is the causative agent of visceral leishmaniasis. It lives and multiplies within the harsh environment of macrophages. In order to investigate how intracellu...
Solid-phase reagents for selective monophosphorylation of carbohydrates and nucleosides.J. Org. Chem. 70(3) , 1100-3, (2005)
Two classes of aminomethyl polystyrene resin-bound linkers of p-acetoxybenzyl alcohol were subjected to reactions with 2-cyanoethyl N,N-diisopropylchlorophosphoramidite to produce the corresponding po...