Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-

Names

[ Name ]:
Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-

Biological Activity

[Description]:

BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

Research Areas >> Inflammation/Immunology

[Target]

STAMBP[1]

[References]

[1]. Bednash JS, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017 May 11;8:15203.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₂N₄O₄S

[ Molecular Weight ]:
508.63

Related Compounds

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