EAAT2 activator 1

Names

[ Name ]:
EAAT2 activator 1

Biological Activity

[Description]:

EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> EAAT2

Research Areas >> Neurological Disease

[Target]

EAAT2[1]

[References]

[1]. Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011;21(19):5774-5777.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₁ClFN₃S

[ Molecular Weight ]:
331.80

Related Compounds

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