Homophthalic acid

Names

[ CAS No. ]:
89-51-0

[ Name ]:
Homophthalic acid

[Synonym ]:
2-(Carboxymethyl)benzoic acid
Benzeneacetic acid, 2-carboxy-
a-Carboxy-o-toluic Acid
MFCD00004326
EINECS 201-913-9
Homophthalic Acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
389.5±17.0 °C at 760 mmHg

[ Melting Point ]:
178-182 °C(lit.)

[ Molecular Formula ]:
C₉H₈O₄

[ Molecular Weight ]:
180.157

[ Flash Point ]:
203.5±17.4 °C

[ Exact Mass ]:
180.042252

[ PSA ]:
74.60000

[ LogP ]:
1.18

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Water Solubility ]:
12 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY1575590

CHEMICAL NAME :: Benzeneacetic acid, 2-carboxy-

CAS REGISTRY NUMBER :: 89-51-0

BEILSTEIN REFERENCE NO. :: 1872069

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H8-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,7,1953

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CY1575590

[ HS Code ]:
2917399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2917399090

[ Summary ]:
2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Catabolism of homophthalic acid by a soil bacterium.

FEMS Microbiol. Lett. 49(2-3) , 305-8, (1989)

A microorganism capable of degrading homophthalic acid as a sole source of carbon was isolated from soil. The strain was tentatively identified as Pseudomonas sp. Oxygen uptake studies were carried ou...

An expeditious and environmentally friendly synthesis of 3-substituted isocoumarins using microwave irradiation.

Nat. Prod. Res. 22(13) , 1120-7, (2008)

A microwave-assisted, environmentally friendly, high-yielding, time-saving synthesis of medicinally important 3-substituted isocoumarins was carried out in a single step by direct condensation of homo...

Metabolic pathway of homophthalic acid in Pseudomonas alcaligenes.

FEMS Microbiol. Lett. 110(1) , 59-64, (1993)

A microorganism capable of degrading homophthalic acid as a sole carbon source was isolated from garden soil. The strain was identified as Pseudomonas alcaligenes. The organism degraded homophthalate ...